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What are the signs and symptoms of sickle cell anemia?.

And signs and symptoms of sickle cell anemia are different. Some people have mild symptoms. Other symptoms are very sharp, and often in the hospital for treatment.

Sickle cell anemia present at birth, but many children do not show any signs until after 4 months of age.

Signs and symptoms most commonly associated with anemia and pain. Signs and other symptoms associated with this disease and complications.
Signs and symptoms related to anemia

The most common symptoms of anemia is fatigue (feeling tired or weak). Other signs and symptoms of anemia include:

* Shortness of breath
* Dizziness
* Headache
* Cold hands and feet
* Pale skin
* Chest pain
Signs and symptoms associated with pain:

Sudden pain in various parts of the body are the symptoms of sickle cell anemia. This pain is called "sickle cell crisis." Sickle cell crises often affect the bones, lungs and abdomen, and joints.

Sickle-cell anemia crisis occurs when the cut sickle red blood cells form clusters in the bloodstream. (Other cells may also play a role in this process vessels.) Blocks of these cells prevent the flow of blood through small blood vessels in the limbs and organs. This can cause pain and damage to the device.

The pain of sickle cell crises can be acute or chronic, but acute pain is more common. Sudden severe pain, and can range from mild to very severe. Pain usually lasts from hours to a few days. Chronic pain, often lasting for weeks or months. Chronic pain can be difficult to bear and mentally draining. This pain may severely limit your daily activities.

Almost all people who have sickle cell anemia and painful crises in some stage of their lives. Some of these crises less than once a year. Others may have 15 or more crises per year.

There are many factors that play a role in sickle cell crisis. In many cases, more than one factor is involved and the exact cause is unknown. You can control some factors. For example, at your own risk increases sickle cell crisis if you are dehydrated (your body does not have enough fluids). Drink plenty of fluids can reduce the risk of painful crisis. There are other factors, such as infection, you can not control it.

Painful crises are the main cause of emergency room visits and hospital of people who have sickle cell anemia.
Complications of sickle cell anemia:

The effects of sickle cell crises in different parts of the body can cause a number of complications.
Hand-foot syndrome:

Sickle cells can block small blood vessels in the hands or feet. This is the condition called hand-foot syndrome. Can lead to pain, swelling, and fever. One or both hands and / or feet can be affected in the same time.

You may feel pain in the bones of many of the hands and feet. Swelling often occurs on the back of the hands and feet and moving to the fingers and feet. In terms of restless leg syndrome may be the first sign of sickle-cell anemia in infants.
Spleen crisis:

The spleen is a device in the abdomen. Usually, it is the liquidation of the abnormal red blood cells and helps fight infection. In some cases, the spleen cells of the trap which should be in the bloodstream. This causes the spleen to a significant increase and lead to anemia.

If the spleen also gets clogged with sickle cell, it will not work right. This can cause the spleen to shrink. If this happens, you may need blood transfusions your body so that it can provide more of the cells and recovery.
Infection:

Children and adults alike who have sickle cell anemia have difficulty in fighting infections. This is because sickle cell anemia can damage the spleen, the organ that helps fight infection.

Infants and young children who are affected by the spleen are more likely to get infections that can kill them within hours or days. Pneumonia is the most common cause of death among young children who have sickle cell anemia.

Meningitis, flu, hepatitis and other diseases that are common in people with sickle cell anemia.
Acute inflammation in the chest:

Acute chest syndrome is the case of life-threatening, linked to sickle cell anemia. It's like pneumonia. The condition is caused by infection or trapped sickle cells in the lungs.

People who have this condition usually have chest pain and fever. They also often have an abnormal chest x-ray results. Over time, the damage caused by Severe Acute Respiratory Syndrome in the chest may lead to a rise in pulmonary arterial hypertension (PAH).
High blood pressure, pulmonary arterial:

Damage to small blood vessels in the lungs makes it difficult for the heart to pump blood through the lungs. This causes the blood pressure in the lungs to rise.

High blood pressure in the lungs is called high blood pressure, pulmonary arterial, or the Public Authority for Housing. Shortness of breath and breathing problems are the main symptoms of the Public Authority for Housing.
Delayed growth and puberty in children:
Children who have sickle cell anemia often grow more slowly than other children. As they reach the age of puberty at a later date. There is a lack of red blood cells and cause the slow growth rate. Adults who have sickle cell anemia often have little or smaller in size than other adults.
Blow:

Two types of stroke can occur in people who have sickle cell anemia. One form occurs when a blood vessel in the brain is blocked. Another example occurs when a blood vessel in the brain bursts.

It can cause a stroke in learning and / or permanent damage to the brain, long-term disability, and paralysis (inability to move), or death.
Eye problems:

Sickle cell and can block small blood vessels that provide oxygen-rich blood to your eyes. This can cause damage in the retina of the eye, thin layers of tissue in the back of your eyes. In the retina take pictures and send them to see the brain.

Without enough blood, will weaken the retina. This can cause serious problems, including blindness.
Priapism:

Males who have sickle cell anemia may be painful erection and unwanted. This is the condition called priapism (Institutional Revolutionary Party, and one in pizm). This happens because the sickle cells block blood flow out of the penis. Over time, priapism can damage the penis and lead to impotence.
Bile:

When the red blood cells die, they release the hemoglobin. The body breaks down this protein to the compound called bilirubin. Too much bilirubin in the body can cause the formation of stones in the gallbladder.

Gallstones may cause constant pain which lasts for 30 minutes or more in the upper right side of the abdomen, and under the right shoulder or between the shoulder blades. Pain may occur after eating fatty meals.

People with gallstones may have nausea in the stomach), vomiting, fever, sweating, chills, clay-colored stools, jaundice (a yellowish color of the skin or whites of the eyes).
Ulcers on the legs:

Sickle-cell ulcers (sores) usually starts small, raised, crusted sores on the lower third of the tibia. Leg ulcers occur more often in males than females. Usually these sores appear between the ages of 10 and 50.

Ulcers caused by sickle-cell disease is not clear. The number of ulcers can vary from one to several. Some heal quickly, but others do not persist for years, or return after healing.
Multiple organ failure:

The failure of many organs of the body is rare, but serious. This can happen if you have a sickle cell crisis, which caused two out of three main organs (lungs, liver, or kidney) to fail.

Symptoms of these complications are fever and changes in mental status, such as fatigue and the sudden loss of interest in your surroundings.