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Sweet(Glycan) play a Role in Cancer Metastasis:-
Cell surface covered with sugar molecules called glycans, that are related to proteins and fats. Sugars from the glycoproteins and glycolipids can take complex forms. In particular, the glycan makeup of normal cells and cancerous epithelial very different. Several studies have suggested that the changes glycan plays a role in metastasis of cancer, although the mechanisms by which it can do so has proved elusive. In a paper published in the Journal of the National Academy of Sciences of the United States, and Dr. Michiko Fukuda, in collaboration with Dr. Minoru Fukuda, has now identified the receptor glycans of cancer of the blood vessels in the lung. These antibodies to cell receptors of skin cancer prevented from entering and growing in the lung. Since the glycan being studied is also expressed on the surface of the colon, breast, lung and ovarian cancer, and these results have broad implications for therapeutic targeting of tumor-related glycan